Detalhe da pesquisa
1.
Respiratory complex I in mitochondrial membrane catalyzes oversized ubiquinones.
J Biol Chem
; 299(8): 105001, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37394006
2.
Killing Two Birds with One Stone: Discovery of Dual Inhibitors of Oxygen and Fumarate Respiration in Zoonotic Parasite, Echinococcus multilocularis.
Antimicrob Agents Chemother
; 67(3): e0142822, 2023 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36840588
3.
Dephospho-Coenzyme A Kinase Is an Exploitable Drug Target against Plasmodium falciparum: Identification of Selective Inhibitors by High-Throughput Screening of a Large Chemical Compound Library.
Antimicrob Agents Chemother
; 66(11): e0042022, 2022 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36314787
4.
Oversized ubiquinones as molecular probes for structural dynamics of the ubiquinone reaction site in mitochondrial respiratory complex I.
J Biol Chem
; 295(8): 2449-2463, 2020 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31953326
5.
Identification of 3,4-Dihydro-2H,6H-pyrimido[1,2-c][1,3]benzothiazin-6-imine Derivatives as Novel Selective Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase.
Int J Mol Sci
; 22(13)2021 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34281290
6.
Discovery of trypanocidal coumarins with dual inhibition of both the glycerol kinase and alternative oxidase of Trypanosoma brucei brucei.
FASEB J
; 33(11): 13002-13013, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31525300
7.
Biochemical studies of membrane bound Plasmodium falciparum mitochondrial L-malate:quinone oxidoreductase, a potential drug target.
Biochim Biophys Acta Bioenerg
; 1859(3): 191-200, 2018 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-29269266
8.
Expression, purification, and crystallization of type 1 isocitrate dehydrogenase from Trypanosoma brucei brucei.
Protein Expr Purif
; 138: 56-62, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28642005
9.
Glycerol kinase of African trypanosomes possesses an intrinsic phosphatase activity.
Biochim Biophys Acta Gen Subj
; 1861(11 Pt A): 2830-2842, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28778484
10.
X-ray crystal structure of the light-independent protochlorophyllide reductase.
Nature
; 465(7294): 110-4, 2010 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-20400946
11.
Structures of cyanobacteriochromes from phototaxis regulators AnPixJ and TePixJ reveal general and specific photoconversion mechanism.
Proc Natl Acad Sci U S A
; 110(3): 918-23, 2013 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23256156
12.
Structure of the trypanosome cyanide-insensitive alternative oxidase.
Proc Natl Acad Sci U S A
; 110(12): 4580-5, 2013 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23487766
13.
Probing the ubiquinol-binding site of recombinant Sauromatum guttatum alternative oxidase expressed in E. coli membranes through site-directed mutagenesis.
Biochim Biophys Acta
; 1837(7): 1219-25, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24530866
14.
Molecular basis for the reverse reaction of African human trypanosomes glycerol kinase.
Mol Microbiol
; 94(6): 1315-29, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25315291
15.
Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria.
Int J Mol Sci
; 16(7): 15287-308, 2015 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26198225
16.
The alternative oxidases: simple oxidoreductase proteins with complex functions.
Biochem Soc Trans
; 41(5): 1305-11, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24059524
17.
Identification and characterization of sialidase-like activity in the developmental stages of Amblyomma variegatum.
J Med Entomol
; 50(1): 85-93, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23427656
18.
Biochemical characterization and identification of ferulenol and embelin as potent inhibitors of malate:quinone oxidoreductase from Campylobacter jejuni.
Front Mol Biosci
; 10: 1095026, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36776743
19.
Alkyl gallates inhibit serine O-acetyltransferase in bacteria and enhance susceptibility of drug-resistant Gram-negative bacteria to antibiotics.
Front Microbiol
; 14: 1276447, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37965540
20.
The role of amino acid residues in the active site of L-methionine γ-lyase from Pseudomonas putida.
Biosci Biotechnol Biochem
; 76(7): 1275-84, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22785484